Identify the vector suitable for cloning long DNA fragments

Options

A. Phage vector
B. Bacterial plasmid
C. Yeast plasmid
D. Cosmids

Answer

To identify the vector suitable for cloning long DNA fragments, we need to analyze the options provided and understand the characteristics of each vector type.

### Step-by-Step Solution:

1. **Understand the Types of Vectors**:
- Vectors are DNA molecules used to carry foreign genetic material into another cell. There are two main types: cloning vectors and expression vectors.

2. **Evaluate the Options**:
- **Farge Vector**: Typically used for cloning smaller DNA fragments, generally up to 10 kb.
- **Bacterial Plasmid**: Commonly used for cloning, but usually can only accommodate DNA segments up to 20 kb.
- **Yeast Plasmid**: Primarily an expression vector, which is not suitable for cloning long DNA fragments. It can express larger segments but is not designed for cloning.
- **Cosmids**: These are hybrid vectors that can carry larger DNA fragments, typically between 28 kb to 50 kb.

3. **Determine the Best Vector**:
- Among the options, Cosmids are specifically designed for cloning larger DNA fragments, making them the most suitable choice for this purpose.

4. **Conclusion**:
- The correct answer is **Cosmids**, as they can effectively clone long DNA fragments ranging from 28 kb to 50 kb.