Which of the following effect is produced by colchicine

Options

A. Duplication of DNA
B. Duplication of chromosomes
C. Formation of spindle fibres
D. Hinderance in the formation of middle wall

Explanation

**Step-by-Step Solution:**

1. **Understanding Colchicine**: Colchicine is an alkaloid derived from the plant Colchicum autumnale, commonly known as meadow saffron. It is a chemical compound that has specific effects on cell division.

2. **Mechanism of Action**: Colchicine works by blocking the assembly of microtubules, which are essential protein fibers necessary for cell division. Microtubules play a crucial role in forming the spindle fibers that separate chromosomes during cell division.

3. **Effects on Cell Division**: By preventing the formation of microtubules, colchicine disrupts the normal process of cell division. This disruption means that the chromosomes cannot pull apart as they normally would during mitosis.

4. **Resulting Effect**: The inability of chromosomes to separate leads to a doubling of the chromosome number in the resulting cells. This process is known as polyploidy, which is often induced in plants for various breeding purposes.

5. **Conclusion**: Therefore, the primary effect produced by colchicine is the duplication of chromosomes due to its interference with microtubule formation during cell division.

**Final Answer**: Colchicine produces the effect of duplication of chromosomes.

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