Acetophenone is prepared from `:`

Options

A. Rosenmund reaction
B. Sandmeyer reaction
C. Wurtz reaction
D. Friedel craft reaction

Answer

To prepare acetophenone, we can use the Friedel-Crafts acylation reaction. Here’s a step-by-step solution to the question:

### Step 1: Identify the Reactants
Acetophenone has the structure C6H5COCH3. To synthesize acetophenone, we need benzene (C6H6) and acetyl chloride (CH3COCl) as our starting materials.

### Step 2: Understand the Friedel-Crafts Acylation
Friedel-Crafts acylation is a reaction where an acyl group is introduced into an aromatic ring. This reaction requires a Lewis acid catalyst, typically anhydrous aluminum chloride (AlCl3).

### Step 3: Set Up the Reaction
1. **Reactants**: Combine benzene (C6H6) and acetyl chloride (CH3COCl) in the presence of AlCl3.
2. **Catalyst**: The AlCl3 acts as a Lewis acid, accepting a pair of electrons from the chlorine atom in acetyl chloride, leading to the formation of a positively charged acylium ion (CH3C^+=O).

### Step 4: Electrophilic Attack
The acylium ion (CH3C^+=O) is a strong electrophile and will attack the benzene ring. The positive charge on the benzene ring allows for the substitution of one hydrogen atom with the acylium ion.

### Step 5: Formation of Acetophenone
Upon the electrophilic substitution, the product formed is acetophenone (C6H5COCH3). During this process, one hydrogen atom from the benzene ring is replaced by the acylium ion, and a molecule of hydrochloric acid (HCl) is released as a byproduct.

### Step 6: Final Product
The final product of this reaction is acetophenone, confirming that acetophenone is prepared from benzene and acetyl chloride through the Friedel-Crafts acylation reaction.

### Conclusion
Thus, acetophenone is prepared from benzene and acetyl chloride in the presence of anhydrous aluminum chloride.

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