During in vitro synthesis of DNA, a researcher used 2',3'- dideoxy cytidine triphosphate as raw nucleotide in place of 2'- deoxy cytidine triphosphate, other conditions remaining as standard. will further polymerisation of DNA continue upto the end or not? Explain.

Explanation

Further polymerisation would not occur, as the 3' OH on sugar is not there to add a new nucleotide for forming ester bond.