What is true about tRNA ?

Options

A. It binds with an amino acid at it 3' end
B. It has five double stranded regions
C. It has a codon at one end which recognizes the anticodon on messenger RNA
D. It looks like clover leaf in the three dimensional structure.

Explanation

To determine what is true about tRNA (transfer RNA), we will analyze the provided statements one by one based on the structure and function of tRNA.

### Step-by-Step Solution:

1. **Statement Analysis**: The first statement claims that tRNA binds with an amino acid at its 3' end.
- **Explanation**: This statement is true. tRNA has a CCA tail at its 3' end where the amino acid attaches. This is essential for the tRNA's function in protein synthesis.

2. **Statement Analysis**: The second statement states that tRNA has five double-stranded regions.
- **Explanation**: This statement is false. tRNA actually has four double-stranded regions, which consist of stem-loop structures.

3. **Statement Analysis**: The third statement claims that tRNA has a codon at one end which recognizes the anticodon on messenger RNA.
- **Explanation**: This statement is incorrect. tRNA contains an anticodon that pairs with the codon on the mRNA. The codon is found on the mRNA, not on the tRNA.

4. **Statement Analysis**: The fourth statement says that tRNA looks like a cloverleaf in three-dimensional structure.
- **Explanation**: This statement is also incorrect. While tRNA does have a cloverleaf structure in two dimensions, its three-dimensional structure is L-shaped.

### Conclusion:
The only true statement about tRNA is that it binds with an amino acid at its 3' end.

### Final Answer:
**The correct statement about tRNA is: It binds with an amino acid at its 3' end.**

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