Abnormal secretion of thyroxine produces

Options

A. Acromegaly
B. Addison's disease
C. Cretinism
D. Goitre.

Answer

### Step-by-Step Solution:

1. **Understanding Thyroxine**:
- Thyroxine is a hormone produced by the thyroid gland that plays a crucial role in regulating metabolism, growth, and development in the body.

2. **Identifying the Question**:
- The question asks about the effects of abnormal secretion of thyroxine. Abnormal secretion can refer to either excessive or insufficient production of this hormone.

3. **Analyzing the Options**:
- **Option A: Acromegaly**:
- This condition is related to the overproduction of growth hormone, not thyroxine. Therefore, it is not the correct answer.
- **Option B: Addison's Disease**:
- This condition is caused by the hyposecretion of cortisol from the adrenal glands, unrelated to thyroxine. Thus, this option is also incorrect.
- **Option C: Cretinism**:
- Cretinism is associated with a deficiency of thyroxine, particularly due to iodine deficiency during pregnancy. However, it specifically refers to low levels of thyroxine and not abnormal secretion in general.
- **Option D: Goiter**:
- Goiter refers to the enlargement of the thyroid gland and can result from both hypersecretion (excess thyroxine) and hyposecretion (deficient thyroxine). This makes it the most relevant condition related to abnormal thyroxine secretion.

4. **Conclusion**:
- Given the analysis, the correct answer to the question about the abnormal secretion of thyroxine is **Goiter** (Option D).