Failure of release of ADH causes

Options

A. Diabetes insipidus
B. Diabetes mellitus
C. Hepatitis
D. Coronary thrombosis.

Answer

**Step-by-Step Solution:**

1. **Understand the Role of ADH**: Antidiuretic hormone (ADH), also known as vasopressin, is produced in the hypothalamus and released from the posterior pituitary gland. Its primary function is to regulate water balance in the body by promoting water reabsorption in the kidneys.

2. **Identify the Consequences of ADH Deficiency**: When there is a failure in the release of ADH, the kidneys cannot reabsorb water effectively. This leads to the production of large volumes of dilute urine.

3. **Recognize the Condition Associated with ADH Deficiency**: The condition characterized by the insufficient release of ADH is known as Diabetes Insipidus. This disorder results in excessive urination (polyuria) and increased thirst (polydipsia).

4. **Differentiate Between Related Conditions**: It is important to distinguish Diabetes Insipidus from Diabetes Mellitus, which is related to insulin deficiency and high blood sugar levels, and does not primarily involve ADH. Hepatitis and coronary thrombosis are unrelated to ADH function.

5. **Conclude with the Correct Answer**: Based on the understanding that the failure of ADH release leads to excessive urination and thirst, the correct answer to the question is Diabetes Insipidus.

**Final Answer**: The failure of release of ADH causes Diabetes Insipidus.

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