Due to deficiency of which hormone, bones become weak in females

Options

A. Progesterone
B. TSH
C. ACTH
D. Oestrogen.

Answer

To solve the question regarding which hormone deficiency leads to weak bones in females, we can follow these steps:

### Step 1: Understand the Question
The question asks about a specific hormone whose deficiency causes weak bones in females. We need to identify the hormone from the given options: progesterone, TSH, ACTH, or estrogen.

### Step 2: Analyze Each Option
- **Progesterone**: This hormone is primarily involved in preparing the endometrium for potential pregnancy after ovulation. It does not play a direct role in bone health.

- **TSH (Thyroid Stimulating Hormone)**: TSH is produced by the pituitary gland and stimulates the thyroid gland to produce thyroid hormones. While thyroid hormones can affect bone metabolism, TSH itself is not directly responsible for bone strength.

- **ACTH (Adrenocorticotropic Hormone)**: ACTH stimulates the adrenal glands to produce cortisol, which is involved in stress response and metabolism regulation. It does not directly affect bone density.

- **Estrogen**: This is a key sex hormone in females that plays a significant role in maintaining bone health. It promotes the activity of osteoblasts, the cells responsible for bone formation. A deficiency in estrogen, particularly during menopause, leads to osteoporosis, a condition characterized by weak and fragile bones.

### Step 3: Identify the Correct Answer
Based on the analysis, the hormone that, when deficient, causes weak bones in females is **Estrogen**.

### Conclusion
The correct answer is **Estrogen**.

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