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Pepsinogen is activated by :...

Pepsinogen is activated by :

A

Chymotrypsin

B

Trypsin

C

HCl

D

Pepsin

Text Solution

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The correct Answer is:
### Step-by-Step Solution: 1. **Understanding Pepsinogen**: Pepsinogen is an inactive precursor (zymogen) of the enzyme pepsin, which is involved in protein digestion in the stomach. 2. **Role of Hydrochloric Acid (HCl)**: When food enters the stomach, the vagus nerve and the hormone gastrin stimulate the secretion of hydrochloric acid (HCl). 3. **Acidic Environment**: The presence of HCl creates an acidic environment in the stomach, which is essential for the activation of pepsinogen. 4. **Activation Process**: The acidic environment (high concentration of hydrogen ions, H⁺) causes pepsinogen to undergo a conformational change, leading to its conversion into the active enzyme pepsin. 5. **Conclusion**: Therefore, the correct answer to the question "Pepsinogen is activated by:" is **HCl (hydrochloric acid)**.
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