Which is correctly matched

Options

A. Central dogma - codon
B. RNA polymerase - RNA primer
C. Okazaki fragments - splicing
D. Restriction enzyme - genetic engineering

Answer

To determine which option is correctly matched, we will analyze each option step by step.

### Step-by-Step Solution:

1. **Understanding Central Dogma:**
- The central dogma of molecular biology describes the flow of genetic information from DNA to RNA to protein. It states that DNA is transcribed into RNA, which is then translated into protein.
- **Match Analysis:** The central dogma is incorrectly matched with "codon." A codon is a sequence of three nucleotides in mRNA that specifies an amino acid, but it is not the central dogma itself.

2. **Analyzing RNA Polymerase:**
- RNA polymerase is an enzyme responsible for synthesizing RNA from a DNA template during transcription.
- **Match Analysis:** If RNA polymerase is matched with "RNA primer," this is incorrect. RNA primers are short RNA sequences that initiate DNA synthesis, not the enzyme itself.

3. **Evaluating Okazaki Fragments and Splicing:**
- Okazaki fragments are short sequences of DNA nucleotides synthesized on the lagging strand during DNA replication. They are later joined together by DNA ligase.
- **Match Analysis:** The term "splicing" refers to the process of removing introns from pre-mRNA and joining exons together. Therefore, matching Okazaki fragments with splicing is incorrect.

4. **Examining Restriction Enzymes:**
- Restriction enzymes are proteins that cut DNA at specific sequences, which makes them essential tools in genetic engineering for cloning and manipulating DNA.
- **Match Analysis:** The match of restriction enzymes with genetic engineering is correct, as they are commonly used in various genetic engineering techniques.

### Conclusion:
Based on the analysis, the correctly matched option is:
**Restriction enzyme is matched with genetic engineering.**