Which is not a pharmaceutical product obtained through biotechnology

Options

A. Human insulin
B. Clotting factor
C. Cholecystokinin
D. Human growth hormone

Answer

**Step-by-Step Solution:**

1. **Understand the Question**: The question asks to identify which of the given options is not a pharmaceutical product obtained through biotechnology.

2. **Evaluate Each Option**:
- **Option 1: Human Insulin**:
- Human insulin is produced through recombinant DNA technology. It was the first genetically engineered product and is widely used in diabetes treatment.
- Conclusion: This option is a pharmaceutical product obtained through biotechnology.

- **Option 2: Clotting Factor**:
- Clotting factor VIII is produced using recombinant DNA technology and is essential for blood clotting. It is also a genetically engineered product.
- Conclusion: This option is a pharmaceutical product obtained through biotechnology.

- **Option 3: Human Growth Hormone**:
- Human growth hormone is secreted by the pituitary gland and can be produced through biotechnology by inserting its cDNA into bacteria (e.g., E. coli).
- Conclusion: This option is a pharmaceutical product obtained through biotechnology.

- **Option 4: Cholecystokinin**:
- Cholecystokinin is a hormone produced in the duodenum that stimulates the contraction of the gallbladder and the release of pancreatic enzymes. It is not produced through genetic engineering or biotechnology.
- Conclusion: This option is NOT a pharmaceutical product obtained through biotechnology.

3. **Final Answer**: The correct answer is **Cholecystokinin** (Option 4), as it is not a product of biotechnology.

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