Which of the following is used to promote growth of new blood vessels, thus helping in wound healing?

Options

A. (a) Humulin
B. (b) TPA
C. (c) TGF-`beta`
D. (d) `alpha` - 1 antitrypsin

Answer

To determine which protein promotes the growth of new blood vessels and aids in wound healing, let's analyze the options provided step by step.

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks for a protein that promotes the growth of new blood vessels, a process known as angiogenesis, which is crucial for wound healing.

2. **Analyzing Option A - Humulin**:
- Humulin is a synthetic form of insulin used to treat diabetes.
- Its primary function is to regulate blood sugar levels, not to promote blood vessel growth.
- **Conclusion**: Humulin is not the correct answer.

3. **Analyzing Option B - TPA (Tissue Plasminogen Activator)**:
- TPA is involved in the breakdown of blood clots.
- It helps dissolve clots that can obstruct blood flow but does not promote the formation of new blood vessels.
- **Conclusion**: TPA is not the correct answer.

4. **Analyzing Option C - TGF-beta (Transforming Growth Factor-beta)**:
- TGF-beta is known to play a significant role in various cellular processes, including the promotion of angiogenesis (the formation of new blood vessels).
- It is involved in tissue repair and wound healing, making it a strong candidate for the answer.
- **Conclusion**: TGF-beta is likely the correct answer.

5. **Analyzing Option D - Alpha-1-antitrypsin**:
- This is a glycoprotein that protects tissues from enzymes of inflammatory cells, particularly in the lungs.
- Its role is more about balancing protease activity rather than promoting blood vessel growth.
- **Conclusion**: Alpha-1-antitrypsin is not the correct answer.

6. **Final Conclusion**: Based on the analysis, the protein that promotes the growth of new blood vessels and aids in wound healing is **C - TGF-beta**.