Clot formation can be prevented by treatment with______in gene therapy

Options

A. DNAase
B. Recombinant vaccine
C. TPA
D. TGF-B

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks which treatment can prevent clot formation in gene therapy. This implies we need to identify a substance or agent that is effective in inhibiting or dissolving blood clots.

2. **Identifying Clot Formation**: Clot formation occurs when blood cells and proteins aggregate to form a solid mass, which can block blood flow. While clotting is a necessary process to prevent blood loss, excessive clotting can lead to serious health issues.

3. **Analyzing the Options**: The question provides four options. We need to evaluate each option to determine which one is relevant to preventing clot formation.

- **Option A: DNAs**: This is an enzyme that cuts DNA. It does not have a role in preventing clot formation.

- **Option B: Recombinant Vaccine**: Vaccines are used to prevent diseases but do not directly affect clot formation.

- **Option C: TPA (Tissue Plasminogen Activator)**: This is a well-known agent that acts as a "clot buster." It activates plasminogen to plasmin, which breaks down fibrin in blood clots, thereby preventing or dissolving clots.

- **Option D: TGF (Transforming Growth Factor)**: This factor is involved in cellular processes and does not specifically prevent clot formation.

4. **Selecting the Correct Option**: After evaluating all options, it is clear that **TPA (Tissue Plasminogen Activator)** is the correct answer because it is specifically designed to prevent or dissolve clots.

5. **Final Answer**: Clot formation can be prevented by treatment with **TPA (Tissue Plasminogen Activator)** in gene therapy.

---