During mitosis, metaphase differ from anaphase in having

Options

A. Same number of chromosome and half number of chromatids
B. Half number of chromatids and half number of chromosomes
C. Half number of chromosomes and same number of chromatids
D. Same number of chromosomes and same number of chromatids

Explanation

To answer the question regarding how metaphase differs from anaphase during mitosis, we need to understand the key characteristics of each phase.

### Step-by-Step Solution:

1. **Understanding Mitosis**: Mitosis is the process of cell division that results in two identical daughter cells. It consists of several phases, including prophase, metaphase, anaphase, and telophase.

2. **Characteristics of Metaphase**:
- During metaphase, chromosomes align at the cell's equatorial plane, also known as the metaphase plate.
- Each chromosome consists of two sister chromatids that are still connected at the centromere.
- The spindle fibers attach to the kinetochores of the chromosomes.

3. **Characteristics of Anaphase**:
- Anaphase follows metaphase. During this phase, the sister chromatids are pulled apart toward opposite poles of the cell.
- This separation results in each pole receiving an equal number of chromosomes.
- At this point, each chromatid is now considered an individual chromosome.

4. **Key Differences**:
- In metaphase, chromosomes are aligned at the metaphase plate and still consist of two sister chromatids.
- In anaphase, the sister chromatids are separated and move toward opposite poles, effectively doubling the number of chromosomes present at each pole.

5. **Conclusion**: The main difference between metaphase and anaphase is that during metaphase, chromosomes are aligned and consist of two sister chromatids, while during anaphase, the sister chromatids are separated and move to opposite poles, resulting in individual chromosomes.

### Final Answer:
During mitosis, metaphase differs from anaphase in having chromosomes aligned at the metaphase plate (two sister chromatids per chromosome) in metaphase, while in anaphase, the sister chromatids are separated and move toward opposite poles, resulting in individual chromosomes.

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