Chemical modification of substance like glycosylation of protein and lipid occur in :-

Options

A. Endoplasmic reticulum
B. Golgi- body
C. Lysosome
D. Ribosome

Answer

To determine where the chemical modification of substances like glycosylation of proteins and lipids occurs, we can analyze the options provided:

1. **Endoplasmic Reticulum (ER)**:
- The ER is involved in protein synthesis and processing, as well as lipid synthesis. However, while some initial modifications occur here, the extensive glycosylation process primarily takes place in another organelle.
- **Hint**: Consider where proteins and lipids undergo further modifications after initial synthesis.

2. **Golgi Body (Golgi Apparatus)**:
- The Golgi body is crucial for processing and modifying proteins and lipids. It is responsible for glycosylation, where carbohydrates are added to proteins and lipids. This modification is essential for the proper functioning and sorting of these molecules for secretion or use within the cell.
- **Hint**: Think about which organelle is known for packaging and modifying proteins and lipids before they are sent to their final destinations.

3. **Lysosome**:
- Lysosomes are primarily involved in the digestion and breakdown of macromolecules, such as carbohydrates, lipids, and proteins. They do not play a significant role in the glycosylation process.
- **Hint**: Remember that lysosomes are more about degradation rather than modification.

4. **Ribosome**:
- Ribosomes are the sites of protein synthesis (translation) but do not modify proteins or lipids. They are not involved in glycosylation.
- **Hint**: Consider the role of ribosomes in protein synthesis rather than modification.

**Conclusion**: The correct answer is the **Golgi Body**, as it is the organelle responsible for the glycosylation of proteins and lipids.

### Summary of Steps:
1. Analyze the role of the Endoplasmic Reticulum in protein and lipid synthesis.
2. Evaluate the Golgi Body's function in modifying proteins and lipids, specifically glycosylation.
3. Consider the functions of lysosomes and ribosomes, noting their lack of involvement in glycosylation.
4. Conclude that the Golgi Body is the correct answer.