Which part of chromosome is concern with ageing of organism and canner.

Options

A. Centromere
B. Telomere
C. Kinetochore
D. Satellite

Answer

### Step-by-Step Solution:

1. **Understanding Chromosomes**: Chromosomes are structures within cells that contain DNA, which carries genetic information. Each chromosome consists of two arms and a centromere.

2. **Identifying Key Components**: The key components of chromosomes include:
- **Telomeres**: These are repetitive nucleotide sequences located at the ends of chromosomes.
- **Centromeres**: The region where two sister chromatids are joined.
- **Kinetochore**: A protein structure that forms on the centromere during cell division.
- **Satellites**: Extra segments of DNA that can be present on chromosomes.

3. **Role of Telomeres**: Telomeres protect the ends of chromosomes from deterioration or fusion with neighboring chromosomes. They are essential for maintaining the integrity of genetic information during cell division.

4. **Telomeres and Ageing**: As cells divide, telomeres shorten. When they become too short, the cell can no longer divide and enters a state known as senescence, which is associated with ageing.

5. **Telomeres and Cancer**: In many cancer cells, telomeres are maintained or lengthened, allowing these cells to divide indefinitely. This uncontrolled division is a hallmark of cancer.

6. **Conclusion**: The part of the chromosome that is concerned with the ageing of the organism and cancer is the **telomere**.