Which does not occurs in prophase?

Options

A. Decondensation of chromatin
B. Condensation of chromatin
C. Appearance of chromosome
D. Disappearance of nuclear membrane and nucleolus

Answer

To determine which event does not occur during prophase, we need to analyze the options provided in the context of the events that take place during this phase of cell division.

### Step-by-Step Solution:

1. **Understand the Events of Prophase**:
- Prophase is the first stage of mitosis where several key changes occur in the cell.

2. **Evaluate Each Option**:
- **Option 1: Decondensation of chromatin**:
- During prophase, chromatin condenses to form visible chromosomes. Decondensation of chromatin is not a characteristic of prophase; it typically occurs during telophase when the chromosomes begin to relax back into chromatin.
- **Option 2: Condensation of chromatin**:
- This is a key event in prophase. The chromatin fibers condense into distinct chromosomes, making them easier to separate during cell division.
- **Option 3: Appearance of chromosomes**:
- As prophase progresses, the chromosomes become visible as distinct entities. This is a hallmark of prophase.
- **Option 4: Disappearance of nuclear membrane and nucleolus**:
- At the end of prophase, the nuclear membrane and nucleolus break down, allowing the chromosomes to interact with the spindle apparatus. This is also an event that occurs during prophase.

3. **Identify the Correct Answer**:
- Among the options, the only event that does not occur during prophase is the **decondensation of chromatin**. This process occurs during telophase.

### Final Answer:
**Decondensation of chromatin does not occur in prophase.**

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