Chromosome exhibit high level of coiling at which phase of karyokinesis :-

Options

A. Prophase
B. Metaphase
C. Telophase
D. Interphase

Answer

To determine at which phase of karyokinesis chromosomes exhibit a high level of coiling, we can analyze the different phases of cell division:

1. **Understanding Karyokinesis**: Karyokinesis is the process of nuclear division that occurs during cell division. It consists of several phases: prophase, metaphase, anaphase, and telophase.

2. **Prophase**: During prophase, chromosomes condense and become visible under a microscope. They start to coil and shorten, but they are not at their maximum coiling yet.

3. **Metaphase**: In metaphase, chromosomes are aligned at the equatorial plate of the cell. At this stage, chromosomes are maximally coiled and condensed, making them the most distinct and easiest to observe. This is where they exhibit the highest level of coiling.

4. **Anaphase**: During anaphase, the sister chromatids are pulled apart toward opposite poles of the cell. While the chromosomes are still visible, they begin to uncoil as they move apart.

5. **Telophase**: In telophase, the chromosomes reach the poles and begin to de-condense back into chromatin. This is the opposite of coiling.

6. **Interphase**: Interphase is the phase where the cell is not dividing, and chromosomes are in a relaxed state, not coiled.

Based on this analysis, the phase of karyokinesis where chromosomes exhibit the highest level of coiling is **metaphase**.

### Final Answer:
**Metaphase**