Division of centromere occurs in :-

Options

A. Prophase
B. Metaphase
C. Anaphase
D. Telophase

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks about the stage in cell division when the centromeres divide. The centromere is the region of a chromosome where the two sister chromatids are joined.

2. **Identifying the Stages of Cell Division**: The main stages of cell division (mitosis) are prophase, metaphase, anaphase, and telophase. Each stage has specific events that occur.

3. **Analyzing Each Stage**:
- **Prophase**: Chromosomes condense and become visible, but the centromeres do not divide at this stage.
- **Metaphase**: Chromosomes align at the metaphase plate, but again, the centromeres remain intact.
- **Anaphase**: This is the stage where the sister chromatids are pulled apart towards opposite poles of the cell. The centromeres divide at this point, allowing the chromatids to separate.
- **Telophase**: The separated chromatids (now individual chromosomes) reach the poles, and the cell begins to divide, but the centromeres have already divided in anaphase.

4. **Conclusion**: The division of centromeres occurs during anaphase, specifically during anaphase II in meiosis when the sister chromatids are separated.

5. **Final Answer**: The division of centromeres occurs in **Option C: Anaphase**.

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