At metaphase, chromosmes are attached to the spindle fibres by their

Options

A. Centromere
B. Satellites
C. Secondary cnstrictions
D. Kinetochores

Answer

To answer the question "At metaphase, chromosomes are attached to the spindle fibres by their," we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Cell Division Phases**:
- Cell division consists of several phases: prophase, metaphase, anaphase, and telophase. Each phase has distinct characteristics and functions.

2. **Identify the Metaphase Characteristics**:
- During metaphase, chromosomes align at the metaphase plate (equatorial plane) of the cell. This is a crucial step for ensuring that each daughter cell will receive an equal set of chromosomes.

3. **Recognize the Role of Spindle Fibers**:
- Spindle fibers are structures that emerge from the centrosomes at the poles of the cell. They play a vital role in separating the chromosomes during cell division.

4. **Determine How Chromosomes Attach to Spindle Fibers**:
- Chromosomes are attached to the spindle fibers at a specific region known as the kinetochore. The kinetochore is a protein structure that forms on the centromere of each chromosome.

5. **Conclusion**:
- Therefore, at metaphase, chromosomes are attached to the spindle fibers by their **kinetochores**.

### Final Answer:
At metaphase, chromosomes are attached to the spindle fibres by their **kinetochores**.

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