Assertion :- Disappearance of nuclear membrane is generally essential for karyokinesis
Reason :- Forward movement of chromosomes is dependent on spindle apparatus, which organise in cytoplasm.

Options

A. If both Assertion & Reason are True & the Reason is a correct explanation of the Assertion.
B. If both Assertion & Reason are True but Reason is not a correct explanation of the Assertion.
C. If Assertion is True but the Reason is False.
D. If both Assertion & Reason are false.

Answer

**Step-by-Step Solution:**

1. **Understanding Karyokinesis:**
- Karyokinesis refers to the process of nuclear division that occurs during cell division. It is essential for the formation of two daughter nuclei from a single parent nucleus.

2. **Assertion Analysis:**
- The assertion states that the disappearance of the nuclear membrane is generally essential for karyokinesis. This is true because, during karyokinesis, the nuclear membrane must break down to allow the chromosomes to align and segregate properly.

3. **Reason Analysis:**
- The reason provided states that the forward movement of chromosomes is dependent on the spindle apparatus, which organizes in the cytoplasm. This is also true because the spindle apparatus is responsible for attaching to the chromosomes and facilitating their movement towards opposite poles of the cell during division.

4. **Connection Between Assertion and Reason:**
- The disappearance of the nuclear membrane allows the spindle apparatus to access the chromosomes, which is crucial for their movement. Without the breakdown of the nuclear membrane, karyokinesis cannot occur effectively.

5. **Conclusion:**
- Both the assertion and the reason are true, and the reason correctly explains the assertion. Therefore, the answer to the question is that both statements are true and the reason is a correct explanation of the assertion.