How many ATP are directly synthesised in glycolysis from one glucose.

Answer

To determine how many ATP are directly synthesized in glycolysis from one glucose molecule, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Glycolysis**: Glycolysis is the metabolic pathway that converts glucose (a six-carbon sugar) into pyruvate (a three-carbon compound). This process occurs in the cytoplasm of the cell.

2. **ATP Production**: During glycolysis, a total of 4 ATP molecules are produced. However, it is important to note that 2 ATP molecules are consumed in the initial steps of glycolysis.

3. **Net ATP Calculation**: To find the net ATP yield from one glucose molecule, we subtract the 2 ATP used from the 4 ATP produced:
- ATP produced = 4
- ATP consumed = 2
- Net ATP = 4 - 2 = 2 ATP

4. **Conclusion**: Therefore, the direct synthesis of ATP in glycolysis from one glucose molecule results in a net gain of 2 ATP.

### Final Answer:
The number of ATP directly synthesized in glycolysis from one glucose molecule is **2 ATP**.