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TCA cycle starts with the condensation o...

TCA cycle starts with the condensation of acetyl group with (A) _____ (B)_____ to yield citric acid.

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**Step-by-Step Solution:** 1. **Understand the TCA Cycle**: The TCA cycle, also known as the Krebs cycle, is a crucial metabolic pathway that plays a key role in cellular respiration. It involves a series of chemical reactions used by all aerobic organisms to generate energy. 2. **Identify the Starting Molecule**: The cycle begins with the condensation of an acetyl group. In this context, the acetyl group comes from acetyl coenzyme A (acetyl-CoA). 3. **Determine the Other Reactant**: The acetyl group does not act alone; it must combine with another molecule to initiate the cycle. The molecule that reacts with the acetyl group is oxaloacetate. 4. **Combine the Reactants**: When acetyl-CoA (which contains the acetyl group) combines with oxaloacetate, they undergo a condensation reaction. This reaction also involves the addition of a water molecule. 5. **Resulting Product**: The condensation of the acetyl group with oxaloacetate yields citric acid (or citrate), which is the first product of the TCA cycle. 6. **Fill in the Blanks**: Based on the above steps, the answer to the question is: - (A) oxaloacetate - (B) water **Final Answer**: TCA cycle starts with the condensation of acetyl group with (A) oxaloacetate (B) water to yield citric acid. ---
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