What would happen when blood is acidic

Options

A. Binding of oxygen with haemoglobin increases
B. Red blood corpuscles are formed in higher number
C. Binding of oxygen with haemoglobin decreases
D. There is no change in oxygen binding nor number of RBC

Answer

**Step-by-Step Solution:**

1. **Understanding Blood Acidity**: Blood becomes acidic primarily due to an increase in carbon dioxide (CO2) concentration. When CO2 levels rise, it reacts with water in the blood to form carbonic acid, which lowers the pH and increases acidity.

2. **Effect on Hemoglobin**: Hemoglobin is the protein in red blood cells responsible for binding oxygen. When blood becomes acidic, the affinity of hemoglobin for oxygen decreases. This means that hemoglobin is less able to bind to oxygen in acidic conditions.

3. **Analyzing the Options**:
- **Option A**: "Binding of oxygen with hemoglobin increases" - This is incorrect because acidic blood decreases the binding affinity.
- **Option B**: "Red blood corpuscles are formed in higher number" - This is also incorrect as acidity does not directly affect the production of red blood cells.
- **Option C**: "Binding of oxygen with hemoglobin decreases" - This is correct as explained; acidic conditions lead to decreased binding affinity.
- **Option D**: "There is no exchange in oxygen binding nor number of RBC" - This is incorrect because while the number of RBCs may not change, the binding of oxygen does change.

4. **Conclusion**: The correct answer is **Option C**: "Binding of oxygen with hemoglobin decreases."

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