Assertion `:-` Carbonic acid is more formed inside the RBC's than the plasma.
Reason `:-` An enzyme carbonic anhydrase is present inside the RBC's

Options

A. If both Assertion & Reason are True & the Reasonn is a correct explanation of the Assertion .
B. If both Assertion & Reason are True but Reason is not a correct explanation of the Assertion
C. If Assertion is True but the Reason is False.
D. If both Assertion & Reason are false.

Answer

**Step-by-Step Solution:**

1. **Understanding the Assertion**: The assertion states that carbonic acid is formed more inside red blood cells (RBCs) than in plasma. This is based on the physiological processes occurring within the body, particularly in the transport of carbon dioxide (CO2).

2. **Role of Hemoglobin**: Hemoglobin, the pigment present in RBCs, plays a crucial role in transporting both oxygen and carbon dioxide. When CO2 enters the RBCs, it undergoes a reaction that leads to the formation of carbonic acid (H2CO3).

3. **Formation of Carbonic Acid**: Inside the RBCs, CO2 reacts with water (H2O) to form carbonic acid, facilitated by the enzyme carbonic anhydrase. This reaction can be represented as:
\[ CO2 + H2O \leftrightarrow H2CO3 \]

4. **Dissociation of Carbonic Acid**: The carbonic acid formed can dissociate into hydrogen ions (H+) and bicarbonate ions (HCO3-):
\[ H2CO3 \leftrightarrow H+ + HCO3- \]
This dissociation is crucial for maintaining pH balance and transporting CO2 in the blood.

5. **Chloride Shift**: The bicarbonate ions (HCO3-) produced inside the RBCs are exchanged with chloride ions (Cl-) from the plasma in a process known as the chloride shift. This mechanism helps in maintaining ionic balance during gas exchange.

6. **Role of Carbonic Anhydrase**: The enzyme carbonic anhydrase is present in high concentrations within RBCs, which accelerates the conversion of CO2 and H2O into carbonic acid. This enzyme is one of the fastest in the body, facilitating the rapid formation of carbonic acid compared to the slower reaction that would occur in the plasma.

7. **Conclusion**: Since carbonic anhydrase is present in RBCs, it explains why more carbonic acid is formed there than in plasma. Therefore, both the assertion and reason are correct, and the reason provides a valid explanation for the assertion.

**Final Answer**: Both the assertion and the reason are correct, and the reason is the correct explanation for the assertion.

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