Excretion of `Na^(+)` in urine is elevated by `:-`

Options

A. ANF
B. ADH
C. ACTH
D. Aldosterone

Answer

To solve the question regarding which factor elevates the excretion of Na⁺ in urine, we will analyze the options provided: ANF, ADH, ACTH, and aldosterone.

### Step-by-Step Solution:

1. **Understanding the Role of Aldosterone**:
- Aldosterone is a hormone produced by the adrenal cortex. It plays a crucial role in the regulation of sodium (Na⁺) and potassium (K⁺) levels in the body.
- When aldosterone is secreted, it promotes the reabsorption of Na⁺ in the kidneys, which typically reduces Na⁺ excretion in urine. Therefore, aldosterone does not elevate Na⁺ excretion.

2. **Analyzing Atrial Natriuretic Factor (ANF)**:
- ANF, or atrial natriuretic factor, is secreted by the heart in response to increased blood volume and pressure.
- Its primary function is to promote the excretion of Na⁺ by the kidneys, leading to increased urine output and reduced blood volume. This means ANF actually elevates Na⁺ excretion.

3. **Examining Antidiuretic Hormone (ADH)**:
- ADH, also known as vasopressin, is responsible for the reabsorption of water in the kidneys.
- It does not directly affect Na⁺ levels; instead, it concentrates urine by retaining water, which can dilute Na⁺ levels but does not promote its excretion.

4. **Considering Adrenocorticotropic Hormone (ACTH)**:
- ACTH is a hormone that stimulates the adrenal cortex but primarily influences cortisol production.
- It does not have a direct role in regulating Na⁺ excretion in the kidneys.

5. **Conclusion**:
- Based on the analysis, the factor that elevates the excretion of Na⁺ in urine is **Atrial Natriuretic Factor (ANF)**.

### Final Answer:
The excretion of Na⁺ in urine is elevated by **ANF**.