Which of the following endocrine glands doesn't work under
regulation of pituitary gland :-
(a) Parathyroid
(b) Thyroid
(c) Adrenal cortex
(d) Adrenal medulla
(e) Testis/Ovary

Options

A. a & b
B. a, d & e
C. b, c & e
D. a & d

Answer

To solve the question of which endocrine gland does not work under the regulation of the pituitary gland, we will analyze each option provided.

### Step-by-Step Solution:

1. **Understanding Endocrine Glands**:
- Endocrine glands are responsible for secreting hormones directly into the bloodstream. The pituitary gland is often referred to as the "master gland" because it regulates many other endocrine glands.

2. **Analyzing Each Option**:
- **(a) Parathyroid**:
- The parathyroid glands secrete parathyroid hormone (PTH), which regulates calcium levels in the blood. They operate independently of the pituitary gland.
- **(b) Thyroid**:
- The thyroid gland produces hormones such as thyroxine (T4) and is regulated by the thyroid-stimulating hormone (TSH) from the pituitary gland.
- **(c) Adrenal Cortex**:
- The adrenal cortex produces hormones like cortisol and aldosterone and is also regulated by the adrenocorticotropic hormone (ACTH) from the pituitary gland.
- **(d) Adrenal Medulla**:
- The adrenal medulla produces adrenaline (epinephrine) and noradrenaline (norepinephrine) and operates independently of the pituitary gland.
- **(e) Testis/Ovary**:
- The gonads (testes and ovaries) produce sex hormones (like testosterone and estrogen) and are regulated by the luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland.

3. **Identifying the Correct Answer**:
- From the analysis, we find that both the **parathyroid gland** and the **adrenal medulla** do not operate under the regulation of the pituitary gland. Therefore, the correct answer is:
- **(a) Parathyroid** and **(d) Adrenal Medulla**.

### Final Answer:
The endocrine glands that do not work under the regulation of the pituitary gland are:
- **(a) Parathyroid** and **(d) Adrenal Medulla**.