During the activation of the amino acid, amino acids bind with the enzyme ......... in the presence of ATP and `Mg^(2+)` and become activated.

Options

A. aminoacyl tRNA synthetase
B. aminoacyl rRNA synthetase
C. aminoacyl mRNA synthetase
D. Both (b) and ( c)

Explanation

To solve the question regarding the enzyme that facilitates the activation of amino acids in the presence of ATP and Mg²⁺, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Activation of Amino Acids**:
- The activation of amino acids refers to the process where amino acids are prepared for incorporation into proteins. This process involves the binding of amino acids to transfer RNA (tRNA).

2. **Identifying the Enzyme**:
- The enzyme responsible for this activation is known as aminoacyl-tRNA synthetase. This enzyme catalyzes the attachment of an amino acid to its corresponding tRNA.

3. **Role of ATP and Mg²⁺**:
- The activation process requires energy, which is provided by ATP. The ATP molecule is hydrolyzed to AMP and pyrophosphate (PPi), which drives the reaction forward.
- Magnesium ions (Mg²⁺) are necessary as they enhance the catalytic activity of the enzyme, allowing it to function more efficiently.

4. **Conclusion**:
- Therefore, the correct answer to the question is that amino acids bind with the enzyme **aminoacyl-tRNA synthetase** in the presence of ATP and Mg²⁺ to become activated.

### Final Answer:
The enzyme is **aminoacyl-tRNA synthetase**.

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