Brunner's glands are located in

Options

A. Mucosa of stomach
B. Pancreas
C. Sub-inucosa of intestine
D. Serosa of rectum

Answer

### Step-by-Step Solution:

1. **Understanding Brunner's Glands**: Brunner's glands are specialized glands that secrete a substance known as mucin, which helps to protect the intestinal lining.

2. **Location of Brunner's Glands**: These glands are primarily located in the submucosa of the duodenum, which is the first part of the small intestine.

3. **Function of Brunner's Glands**: The main function of Brunner's glands is to secrete alkaline mucin. This secretion helps to neutralize the acidic chyme that comes from the stomach into the duodenum, preventing damage to the intestinal lining.

4. **Correct Answer Identification**: Given the options:
- Mucosa of stomach
- Pancreas
- Submucosa of intestine
- Mucosa of intestine
- Serosa of rectum

The correct answer is **Submucosa of intestine** (specifically in the duodenum).

5. **Conclusion**: Therefore, Brunner's glands are located in the submucosa of the small intestine (duodenum).