Cori's cycle involves

Options

A. Gluconeogenesis in the muscle
B. Deamination in the liver
C. Gluconeogenesis in the liver
D. Urea synthesis in the liver

Answer

**Step-by-Step Solution:**

1. **Understanding Cori's Cycle**: Cori's cycle, also known as the lactic acid cycle, is a metabolic pathway that plays a crucial role in energy production during anaerobic conditions.

2. **Anaerobic Glycolysis in Muscles**: During intense exercise or anaerobic conditions, glucose is broken down in the muscles through a process called glycolysis. This process converts glucose into pyruvate.

3. **Conversion to Lactic Acid**: In the absence of sufficient oxygen, pyruvate is then converted into lactic acid (or lactate) in the muscles. This accumulation of lactic acid can lead to muscle fatigue.

4. **Transport to the Liver**: The lactic acid produced in the muscles is released into the bloodstream and transported to the liver.

5. **Gluconeogenesis in the Liver**: In the liver, lactic acid undergoes a process called gluconeogenesis, where it is converted back into glucose. This newly formed glucose can then be released back into the bloodstream to be used as an energy source by the muscles.

6. **Cycle Completion**: The cycle continues as the glucose produced in the liver can be taken up by the muscles again for energy, thus completing the Cori cycle.

**Final Summary**: Cori's cycle involves glycolysis in the muscles, where glucose is converted to lactic acid, and gluconeogenesis in the liver, where lactic acid is converted back to glucose.

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