Which of the following conformation will be the most stable?`

Options

A.
B.
C.
D.

Answer

To determine which conformation is the most stable among the given options, we need to analyze the different conformations of the molecule, particularly focusing on the positions of the bulky groups (in this case, methyl groups).

### Step-by-Step Solution:

1. **Identify the Conformations**:
- We have four different conformations to analyze. Typically, these include staggered and eclipsed conformations. Staggered conformations have groups positioned at maximum distance from each other, while eclipsed conformations have groups overlapping.

2. **Understand Staggered vs. Eclipsed Conformations**:
- Staggered conformations are generally more stable than eclipsed conformations due to reduced steric hindrance and torsional strain. In staggered conformations, bulky groups are positioned as far apart as possible.
- Eclipsed conformations, on the other hand, have bulky groups overlapping, leading to increased steric hindrance and torsional strain, making them less stable.

3. **Analyze the Specific Conformations**:
- Among the conformations, we need to identify which one has the bulky groups (methyl groups) positioned opposite to each other. This arrangement is known as the anti-conformation.
- The anti-conformation is the most stable because it minimizes steric interactions between the bulky groups.

4. **Determine the Most Stable Conformation**:
- Based on the analysis, the conformation where the methyl groups are positioned opposite to each other (anti-conformation) will be the most stable. This is typically the first option in many problems.

5. **Conclusion**:
- The most stable conformation is the one where the bulky groups (methyl groups) are in the anti position, which is option 1.

### Final Answer:
The most stable conformation is **Option 1**.