Home
Class 12
CHEMISTRY
The product formed in the reaction of gl...

The product formed in the reaction of glycine with benzoyl chloride `+aq. NaOH` is

A

`PhCOCH_(2)NH_(2)`

B

`PhCH_(2)NH_(2)`

C

`PhCONHCH_(3)`

D

`PhCONHCH_(2)CO_(2)H`

Text Solution

AI Generated Solution

The correct Answer is:
To determine the product formed in the reaction of glycine with benzoyl chloride in the presence of aqueous NaOH, we can follow these steps: ### Step 1: Identify the Reactants - Glycine (NH2CH2COOH) is an amino acid with an amino group (-NH2) and a carboxylic acid group (-COOH). - Benzoyl chloride (C6H5COCl) is an acyl chloride, which can react with nucleophiles. ### Step 2: Understand the Reaction Mechanism - The amino group (-NH2) of glycine acts as a nucleophile and attacks the carbonyl carbon of benzoyl chloride. - This is a nucleophilic acyl substitution reaction, which can be classified as an SN2 mechanism due to the nature of the reactants. ### Step 3: Reaction Process 1. The nitrogen atom in the amino group of glycine attacks the carbonyl carbon of benzoyl chloride. 2. This leads to the formation of a tetrahedral intermediate, where the chlorine atom (Cl) is displaced as a leaving group. 3. The tetrahedral intermediate collapses, resulting in the formation of an amide bond. ### Step 4: Write the Product - The product formed from this reaction is an amide. The structure can be represented as: - The carbonyl group from benzoyl chloride remains, and the nitrogen from glycine is now bonded to the carbonyl carbon. - The final product is benzamide with a glycine side chain, which can be written as: - C6H5CONHCH2COOH (benzyloxyacetic acid). ### Final Product - The product formed is **benzoylglycine**, which can also be represented as **C6H5CONHCH2COOH**.

To determine the product formed in the reaction of glycine with benzoyl chloride in the presence of aqueous NaOH, we can follow these steps: ### Step 1: Identify the Reactants - Glycine (NH2CH2COOH) is an amino acid with an amino group (-NH2) and a carboxylic acid group (-COOH). - Benzoyl chloride (C6H5COCl) is an acyl chloride, which can react with nucleophiles. ### Step 2: Understand the Reaction Mechanism - The amino group (-NH2) of glycine acts as a nucleophile and attacks the carbonyl carbon of benzoyl chloride. ...
Promotional Banner

Topper's Solved these Questions

  • NITROGEN CONTAINING COMPOUNDS

    ERRORLESS |Exercise PROPERTIES OF NITROGEN CONTAINING COMPOUNDS|16 Videos
  • NITROGEN CONTAINING COMPOUNDS

    ERRORLESS |Exercise TESTS FOR NITROGEN CONTAINING COMPOUNDS|11 Videos
  • NITROGEN CONTAINING COMPOUNDS

    ERRORLESS |Exercise JEE (ADVANCED) 2018 MORE THAN ONE CHOICE CORRECT ANSWER|1 Videos
  • IONIC EQUILIBRIUM

    ERRORLESS |Exercise JS Jee Section (JEE Advanced (Numeric answer type question))|1 Videos
  • NUCLEAR CHEMISTRY

    ERRORLESS |Exercise JEE SECTION (Matrix Match Type Questions)|2 Videos

Similar Questions

Explore conceptually related problems

The product formed by the reaction of acetamide with bromine in presence of NaOH is

Name the electrophile produced in the reaction of benzene with benzoyl chloride in the presence of anhydrous AlCl_(3) . Name the reaction also.

The major products formed in the reaction of toluene with chlorine in the presence of ferric chloride are :

The product formed in the reaction of SOCl_2 (thionyl chloride) with white phosphorous is.

Reaction of aniline with acety1 chloride in the presence of NaOH gives .

Knowledge Check

  • Reaction of aniline with benzoyl chloride gives :

    A
    Benzoin
    B
    Benzanilide
    C
    Benzanide
    D
    None of these
  • The product formed by the reaction of acetamide with bromine in presence of NaOH is

    A
    `CH_3CN`
    B
    `CH_3CHO`
    C
    `CH_3CH_2OH`
    D
    `CH_3NH_2`
  • The major products formed in the reaction of toluene with chlorine in the presence of ferric chloride are :

    A
    o-chlorotoluene
    B
    m-chlorotoluene
    C
    p-chlorotoluene
    D
    benzyl chloride
  • ERRORLESS -NITROGEN CONTAINING COMPOUNDS -PREPARATION OF NITROGEN CONTAINING COMPOUNDS
    1. Complete the following reaction: RNH(2)+H(2)SO(4)to

      Text Solution

      |

    2. n-Propylamine yields a volatile compound X on warning with alc alkali ...

      Text Solution

      |

    3. The product formed in the reaction of glycine with benzoyl chloride +a...

      Text Solution

      |

    4. Action of NaNO(2)+dil HCl on ArNH(2) yields ArN(2)^(+)Cl^(-). A simila...

      Text Solution

      |

    5. Which one of the following nitro compounds when react with nitrous aci...

      Text Solution

      |

    6. Which of the following has the smell of bitter almonds

      Text Solution

      |

    7. Identify the product C in the series. C(6)H(5)NO(2) overset(FeHCl) t...

      Text Solution

      |

    8. A compound with nitro group was reduced by Sn//HCl, followed by treatm...

      Text Solution

      |

    9. The reduction of which of the following compound would yield secondary...

      Text Solution

      |

    10. Dye test can be used to distinguish between

      Text Solution

      |

    11. Text Solution

      |

    12. Which of the following is not the property of ethanenitrile (CH3CN) ?

      Text Solution

      |

    13. Amino group, -NH(2) is ortho, para-directing group in case of aromatic...

      Text Solution

      |

    14. Aniline reacts with alktl halide to give

      Text Solution

      |

    15. When an organic compound was treated with sodium nitrite and hydrochlo...

      Text Solution

      |

    16. Among the following compounds nitrobenzene, benzene, aniline and pheno...

      Text Solution

      |

    17. Which of the following compounds does not react with NaNO2 and HCl?

      Text Solution

      |

    18. Aniline when treated with conc. HNO3 gives

      Text Solution

      |

    19. Amines behave as:

      Text Solution

      |

    20. Mixture of benzene and aniline can be separated by:

      Text Solution

      |