Alpha thalassemia is controlled by

Options

A. one gene located on chromosome 11
B. one gene located on chromosome 16
C. two gene located on chromosome 11
D. two gene located on chromosome 16

Answer

To answer the question regarding what controls alpha thalassemia, we can break down the information step by step.

### Step-by-Step Solution:

1. **Understanding Alpha Thalassemia**:
- Alpha thalassemia is a blood disorder that affects the production of hemoglobin, which is essential for transporting oxygen in the blood.

2. **Genetic Basis**:
- The disorder is caused by mutations in the genes that are responsible for producing the alpha chains of hemoglobin.

3. **Chromosomal Location**:
- The genes responsible for alpha thalassemia are located on chromosome 16. Specifically, there are two genes involved in the production of alpha globin chains.

4. **Inheritance Pattern**:
- Alpha thalassemia is inherited in an autosomal recessive manner, meaning that two copies of the mutated gene (one from each parent) are necessary for the disease to manifest.

5. **Conclusion**:
- Therefore, alpha thalassemia is controlled by the genes located on chromosome 16, specifically the alpha globin genes (HBA1 and HBA2).

### Final Answer:
Alpha thalassemia is controlled by genes located on chromosome 16.

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