Select the odd one with respect to the chemical nature of a hormone ?

Options

A. Peptide and polypeptide
B. Steroid and iodothyronine
C. Steroids and amino acid derivative
D. Nucleic and derivatives

Answer

To solve the question "Select the odd one with respect to the chemical nature of a hormone," we need to analyze the given options based on their chemical classifications.

### Step-by-Step Solution:

1. **Identify the Options**: The options provided are:
- Peptide and Polypeptide
- Steroid and Iodothyronine
- Steroid and Amino Acid Derivative
- Nucleic Acid and Derivative

2. **Analyze Peptide and Polypeptide**:
- Peptide hormones are made up of short chains of amino acids, while polypeptide hormones are longer chains of amino acids. Both belong to the same category of hormones (protein-based).
- **Conclusion**: These two are similar in chemical nature.

3. **Analyze Steroid and Iodothyronine**:
- Steroid hormones are derived from cholesterol and include hormones produced by the adrenal cortex, testes, and ovaries.
- Iodothyronines, such as T3 and T4, are thyroid hormones that contain iodine.
- **Conclusion**: Both are distinct classes of hormones but are not similar to peptide hormones.

4. **Analyze Steroid and Amino Acid Derivative**:
- Steroid hormones are derived from cholesterol, while amino acid derivatives (like epinephrine and norepinephrine) are derived from amino acids.
- **Conclusion**: These two are fundamentally different in their chemical structure.

5. **Analyze Nucleic Acid and Derivative**:
- Nucleic acids (DNA and RNA) are not hormones but are the genetic materials. Their derivatives do not classify as hormones.
- **Conclusion**: This option is also different from the others.

6. **Identify the Odd One Out**:
- The odd one out is "Steroid and Amino Acid Derivative" because steroids and amino acid derivatives represent two different classes of hormones, while the other pairs have similarities or are related in some way.

### Final Answer:
The odd one with respect to the chemical nature of a hormone is **Steroid and Amino Acid Derivative**.