What are the steps of the endomembrane system ?

Options

A. The proteins and lipids get wrapped in a vesicle , drifted to Golgi , attach to cis - Golgi , move through Golgi , exit trans - Golgi in a new vesicle , drift to the cell membrane , and exocytosis .
B. The proteins and lipids get wrapped in a vesicle , drifted to the endosplasmic reticulum , attach to trans Golgi , move through Golgi , exit cis Golgi in a new vesicle , drift to the cell membrane , and exocytosis .
C. The carbohydrates and lipids get warpped in a vesicle , drifted to Golgi , attach to cis Golgi , move through Golgi , exit trans Golgi in a new vesicle , drift to the cell membrane , and exocytosis .
D. The nucleic acids and lipids get wrapped in a vesicle , drifted to the endoplasmic reticulum, attach to trans Golgi , move through Golgi , exit cis Golgi in a new vesicle , drift to the cell membrane , and exocytosis .

Answer

To answer the question about the steps of the endomembrane system, we can break down the process into a series of steps that involve various organelles within the cell. Here’s a step-by-step explanation:

### Step-by-Step Solution:

1. **Synthesis of Proteins and Lipids**:
- The process begins in the **endoplasmic reticulum (ER)**, which has two types: rough ER and smooth ER. The rough ER is involved in synthesizing proteins due to the presence of ribosomes, while the smooth ER is responsible for lipid synthesis.

2. **Formation of Vesicles**:
- Once proteins and lipids are synthesized, they are packaged into small membrane-bound sacs called **vesicles**. This wrapping is essential for transporting these molecules to their next destination.

3. **Transport to the Golgi Apparatus**:
- The vesicles then **drift** towards the **Golgi apparatus**. This organelle is responsible for modifying, sorting, and packaging proteins and lipids for secretion or delivery to other organelles.

4. **Entry into the Golgi Apparatus**:
- The vesicles **attach to the cis-Golgi network**, which is the receiving side of the Golgi apparatus. Here, the contents are processed and modified.

5. **Processing in the Golgi Apparatus**:
- As the vesicles move through the Golgi apparatus from the cis to the trans side, the proteins and lipids undergo various modifications, such as glycosylation (addition of sugar molecules).

6. **Exit from the Golgi Apparatus**:
- After processing, the modified proteins and lipids exit the Golgi apparatus from the **trans-Golgi network** in new vesicles.

7. **Transport to the Cell Membrane**:
- These vesicles then **drift towards the cell membrane**.

8. **Exocytosis**:
- Finally, the vesicles fuse with the cell membrane, and the contents are released outside the cell through a process called **exocytosis**. This is how large amounts of proteins and lipids are secreted from the cell.

### Conclusion:
The correct sequence of steps in the endomembrane system involves the synthesis of proteins and lipids in the ER, packaging into vesicles, transport to the Golgi apparatus, processing, and finally exocytosis.