Which of the following compounds not react with sodium bisulphite

Options

A. Benzaldehyde
B. Acetone
C. Acetophenone
D. Acetaldehyde

Explanation

To determine which compound does not react with sodium bisulfite (NaHSO3), we need to analyze the reactivity of the given compounds based on their structure, particularly focusing on carbonyl compounds (aldehydes and ketones).

### Step-by-Step Solution:

1. **Understanding Sodium Bisulfite Reaction**:
- Sodium bisulfite reacts with carbonyl compounds (aldehydes and ketones) to form a bisulfite adduct. The nucleophilic bisulfite ion (HSO3-) attacks the electrophilic carbonyl carbon.

2. **Identifying the Compounds**:
- We need to evaluate the reactivity of the following compounds:
- A) Benzaldehyde
- B) Acetone
- C) Acetophenone
- D) Acetaldehyde

3. **Analyzing Each Compound**:
- **A) Benzaldehyde**:
- Benzaldehyde is an aldehyde. Aldehydes readily react with sodium bisulfite to form adducts. Therefore, benzaldehyde will react.

- **B) Acetone**:
- Acetone is a ketone with a methyl group (ketomethyl). It is the simplest ketone and can react with sodium bisulfite to form an adduct. Thus, acetone will react.

- **C) Acetophenone**:
- Acetophenone is also a ketone, but it has a phenyl group attached. The presence of the bulky phenyl group introduces significant steric hindrance, making it difficult for the bisulfite ion to effectively attack the carbonyl carbon. Therefore, acetophenone does not react with sodium bisulfite.

- **D) Acetaldehyde**:
- Acetaldehyde is another aldehyde and will react with sodium bisulfite to form an adduct. Thus, acetaldehyde will react.

4. **Conclusion**:
- Among the given options, **acetophenone (C)** is the compound that does not react with sodium bisulfite due to steric hindrance caused by the bulky phenyl group.

### Final Answer:
**C) Acetophenone does not react with sodium bisulfite.**

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