Explain the significance of origin of replication and selectable market in gene cloning experiments .

Explanation

Origin of replication : This is a sequence from where replication starts and any piece of DNA when linked to this sequence can be made to replicate within the host cells. This sequence is also responsible for controlling the copy number of the linked DNA.
Selectable marker : The sequence of DNA , which helps in indentifying and eliminating non transformants and selectively permitting the growth of the transformants .