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(a) Explain Griffith’s series of exeerim...

(a) Explain Griffith’s series of exeeriments where he witnessed transformatio in bacteria he worked with.
(b) Name the scientists responsible for determining the biochemical nature I “transforming principle” in Griffith’s experiments. What did they prove ?

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### Step-by-Step Text Solution #### (a) Explanation of Griffith’s Series of Experiments 1. **Background**: Frederick Griffith conducted experiments in 1928 using two strains of the bacterium *Streptococcus pneumoniae*: a virulent (disease-causing) strain and a non-virulent (harmless) strain. 2. **Experimental Setup**: - Griffith injected mice with different combinations of these bacterial strains: ...
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(a) Explain Griffith's series of experiments where he witnessed transformation in bacteria he worked with. (b) Name the scientists responsible for determining the biochemical nature of "transforming principle" in Griffith's experiments. What did they prove?

(a) Describe the various steps of Griffith's experiment that led to the conclusion of the 'Transforming Principle'. (b) How did the chemical nature of the 'Transforming Principle' get established ?

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Answer the following questions based on Meselson and Stahl s experiment: (a) Write the name of the chemical substance used as a source of nitrogen in the experiment by them. (b) Why did the scientists synthesise the light and the heavy DNA molecules In the organism used in the experiment ? (c) How did the scientists make it possible to distinguish the heavy DNA molecule from the light DNA molecule ? Explain. ((1) Write the conclusion the scientists arrived at after completing the experiment.

Explain the experiment performed be Griffith on Streptococcus pneumonia. What did he conclude from this experiment? Name the three scientists who followed up Griffith's experiments. What did they conclude and how?

Assertion : In Griffith's experiment, a mixture of heat-killed virulent bacteria R and live non - virulent bacteria S, lead to the death of mice. Reason : 'Transforming principle' got transferred from heat -killed R strain and made it virulent.

(a) state the central dogma as proposed by francis crick are there any exceptions to it ? Suppport your answer with a reason and an example (b) Explain how the biochemical chraterisation (nature) of Transforming pronciple was determined which was not defined from Griffith 's experiments