What happens when chromatids fail to segregate during cell division cycle ?
Explain your answer with an example.

Explanation

### Step-by-Step Solution:

1. **Understanding Chromatid Segregation**: During cell division, specifically in mitosis and meiosis, chromatids (the two identical halves of a duplicated chromosome) must separate and move to opposite poles of the cell. This process is crucial for ensuring that each daughter cell receives the correct number of chromosomes.

2. **Failure of Segregation**: When chromatids fail to segregate properly, this leads to a situation where one daughter cell may receive an extra chromosome, while the other may receive none. This phenomenon is known as nondisjunction.

3. **Consequences of Nondisjunction**: The failure of chromatids to segregate can result in aneuploidy, which is an abnormal number of chromosomes in a cell. This can manifest as either:
- **Gain of Chromosomes**: An extra chromosome is present (e.g., 47 chromosomes instead of the normal 46).
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