The chromosomes are shortest and thickest during

Options

A. Anaphase
B. Metaphase
C. Telophase
D. Interphase

Answer

To determine when chromosomes are shortest and thickest, we need to analyze each phase of cell division:

### Step-by-Step Solution:

1. **Understanding Chromosome Structure**:
- Chromosomes are made up of DNA and proteins. They undergo changes in structure during different phases of the cell cycle.

2. **Identifying the Phases**:
- The main phases of cell division include Interphase, Prophase, Metaphase, Anaphase, and Telophase.

3. **Analyzing Anaphase**:
- In Anaphase, the centromeres divide, and sister chromatids are pulled apart towards opposite poles of the cell. At this stage, chromosomes are not at their shortest or thickest.
- **Conclusion**: Anaphase is **not** the correct answer.

4. **Analyzing Metaphase**:
- During Metaphase, chromosomes are aligned along the equatorial plane of the cell. They are condensed, making them appear short and thick. This is the stage where chromosomes are most visible and in their most compact form.
- **Conclusion**: Metaphase is the correct answer.

5. **Analyzing Telophase**:
- In Telophase, the nuclear membrane reforms around the separated chromatids, and chromosomes begin to de-condense. They are not at their shortest or thickest during this phase.
- **Conclusion**: Telophase is **not** the correct answer.

6. **Analyzing Interphase**:
- Interphase is the preparatory phase for cell division, where the cell grows and DNA is replicated. Chromosomes are in a relaxed state (chromatin) and not condensed.
- **Conclusion**: Interphase is **not** the correct answer.

### Final Answer:
The chromosomes are shortest and thickest during **Metaphase** (Option B).

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