Number of acetyl CoA formed from one molecule of glucose is

Options

A. 1
B. 2
C. 4
D. 6

Answer

To determine the number of acetyl CoA molecules formed from one molecule of glucose, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Starting Molecule**:
- The starting molecule is glucose, which is a 6-carbon compound.

2. **Understand Glycolysis**:
- Glucose undergoes glycolysis, a metabolic pathway that breaks down glucose into two molecules of pyruvic acid (pyruvate). This process occurs in the cytoplasm and results in the production of energy (ATP).

3. **Conversion of Pyruvate to Acetyl CoA**:
- Each molecule of pyruvate (which is a 3-carbon compound) is then converted into acetyl CoA. This conversion occurs in the mitochondria and is facilitated by the enzyme pyruvate dehydrogenase.

4. **Calculate the Number of Acetyl CoA Molecules**:
- Since one molecule of glucose produces two molecules of pyruvate, and each pyruvate is converted into one molecule of acetyl CoA, the total number of acetyl CoA produced from one molecule of glucose is:
- 2 pyruvate × 1 acetyl CoA/pyruvate = 2 acetyl CoA

5. **Conclusion**:
- Therefore, the number of acetyl CoA formed from one molecule of glucose is **2**.

### Final Answer:
The number of acetyl CoA formed from one molecule of glucose is **2**.

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