Protein deficiency leads to `:`

Options

A. kwashiorkar
B. marasmus
C. Cretinism
D. both (1) and (2)

Answer

### Step-by-Step Solution:

1. **Understanding Protein Deficiency**: Protein deficiency occurs when there is an inadequate intake of protein in the diet. This can lead to various health issues and diseases.

2. **Identifying the Options**: The options given are:
- A. Kwashiorkor
- B. Marasmus
- C. Cretinism
- D. Both 1 & 2 (Kwashiorkor and Marasmus)

3. **Analyzing Kwashiorkor**: Kwashiorkor is a severe form of malnutrition that specifically results from a deficiency of protein. It is commonly found in regions where there is a lack of protein-rich foods. Symptoms can include edema, irritability, and an enlarged liver.

4. **Analyzing Marasmus**: Marasmus is a form of malnutrition that results from a deficiency of calories and nutrients in general, not specifically protein. It leads to severe weight loss and muscle wasting.

5. **Analyzing Cretinism**: Cretinism is a condition caused by a deficiency of iodine, which affects thyroid hormone production. It is unrelated to protein deficiency.

6. **Conclusion**: Based on the analysis, the correct answer to the question "Protein deficiency leads to:" is **A. Kwashiorkor**.