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Which of the following amino acid substi...

Which of the following amino acid substitution is responsible for causing sickle cell anemia?

A

Valine is substituted by Glutamic acid in the `alpha` globin chain at the sixth position

B

Valine is substituted by Glutamic acid in the `beta` globin chain at seventh position

C

Glutamic acid is substituted by Valine in the `alpha` globin chain at the sixth position

D

Glutamic acid is substituted by Valine in the `beta` globin chain at the sixth position

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