How many of the following are examples of hormones which interact with intracellular receptors ?
( Cortisol, testosterone, estradiol , thyroxine ,insulin , epinephrine )

Options

A. 5
B. 4
C. 6
D. 3

Answer

To determine how many of the listed hormones interact with intracellular receptors, we will analyze each hormone based on their mechanism of action.

### Step-by-Step Solution:

1. **Understanding Intracellular Receptors**:
- Intracellular receptors are located inside the cell and are typically activated by lipid-soluble hormones that can easily cross the cell membrane.

2. **Analyzing Each Hormone**:
- **Cortisol**: This is a steroid hormone that can pass through the cell membrane and bind to intracellular receptors.
- **Testosterone**: Another steroid hormone that also interacts with intracellular receptors.
- **Estradiol**: This is a form of estrogen, which is also a steroid hormone and interacts with intracellular receptors.
- **Thyroxine (T4)**: This thyroid hormone is lipid-soluble and can bind to intracellular receptors.
- **Insulin**: This is a peptide hormone and does not cross the cell membrane; it binds to receptors on the cell surface.
- **Epinephrine (Adrenaline)**: This is a catecholamine and is not lipid-soluble; it primarily binds to cell surface receptors.

3. **Counting the Hormones**:
- The hormones that interact with intracellular receptors are:
- Cortisol
- Testosterone
- Estradiol
- Thyroxine
- Therefore, there are 4 hormones that interact with intracellular receptors.

### Final Answer:
The number of hormones that interact with intracellular receptors from the given list is **4**.

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