Colchicine is a chemical that stop chromatids from separating during mitosis. If a cell is treated with colchicine , at which stage of mitosis will this cell reach but not complete ?

Options

A. Anaphase
B. Metaphase
C. Telophase
D. Cytokinesis

Answer

To solve the question regarding the effect of colchicine on mitosis, we need to understand the stages of mitosis and the role of colchicine in this process.

### Step-by-Step Solution:

1. **Understanding Mitosis**: Mitosis is the process of cell division that results in two daughter cells with the same genetic material as the parent cell. The stages of mitosis are prophase, metaphase, anaphase, telophase, and cytokinesis.

2. **Role of Colchicine**: Colchicine is a chemical that inhibits the separation of chromatids during mitosis. This means that it prevents the chromatids from moving apart during the anaphase stage.

3. **Identifying the Stage Affected**: Since colchicine stops chromatids from separating, we need to identify at which stage of mitosis this would occur. The separation of chromatids occurs specifically during anaphase.

4. **Determining the Stage Reached but Not Completed**: If a cell is treated with colchicine, it will reach the stage just before anaphase, which is metaphase. In metaphase, the chromosomes are aligned at the equatorial plane of the cell, and the chromatids are still connected at the centromere.

5. **Conclusion**: Therefore, if a cell is treated with colchicine, it will reach the metaphase stage but will not be able to proceed to anaphase due to the inhibition of chromatid separation.

### Final Answer:
The cell will reach the **metaphase** stage of mitosis but will not complete the process.